Occult hepatitis B in Egyptian thalassemic children

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Occult hepatitis B in Egyptian thalassemic children.

INTRODUCTION Thalassemia is hereditary anemia which requires lifelong transfusion as treatment, and hepatitis viral infection is one of the risks of repeated transfusions. Hepatitis B outbreaks in health-care settings are still a serious public health concern worldwide. Blood samples negative for HBsAg but positive for HBV-DNA, with or without the presence of HBV antibodies, are classified as "...

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Occult Hepatitis B in Patients Undergoing Chemotherapy

Introduction: The hepatitis B virus (HBV) is one health problem in Iran. Occult hepatitis B (OBI) is diagnosed by the detection of HBV DNA in the serum or liver tissue of patients for whom other serology, especially HBsAg and HBcAg, are negative. The current study aimed to determine the prevalence of OBI in patients who refer for chemotherapy. Methods: Al...

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Occult hepatitis B infection in Egyptian health care workers.

We tested the frequency of occult hepatitis B infection (OBI) among Egyptian healthcare workers (HCWs). We tested 132 HCWs for hepatitis B virus (HBV) DNA by nested polymerase chain reaction (PCR), and hepatitis C virus antibody (anti-HCV) by ELISA. HCV RNA was measured by nested PCR in anti-HCV-positive HCWs. HBV-DNA-positive HCWs were subjected to HBV genotyping. We included 132 HCWs who were...

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Immunogenicity of recombinant hepatitis B vaccine in thalassemic children.

The plasma derived vaccine for hepatitis B became commercially available in 1982 but its availability was limited. The new generation of hepatitis B vaccine (recombinant rDNA yeast derived) can be produced in greater quantities at a comparable cost. Recombinant HBV vaccine given in infancy is highly immunogenic. Most infants develop antibody titre well above 10 m1U/ml, the level associated with...

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prevalence of hepatitis B among thalassemic patients in Kerman

A prospective case control study was carried out to evaluate the prevalence of HBsAg in 129 thalassemic patients and 113 children as a control group.ELISA was used for serologic investigations. thalassemic  patients were aged 8.5+_3.8 years and children of the control group were aged 7.2+_3.8 years.48.1% of the case group and 36.3% of the control group were female and 51.9% of the case group an...

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ژورنال

عنوان ژورنال: The Journal of Infection in Developing Countries

سال: 2011

ISSN: 1972-2680

DOI: 10.3855/jidc.1706